Valtrax Research is opening — leave your email and we'll ping you the moment the first compounds are listed.
Every lot tested by Janoshik Analytical
Cart
Your cart is empty
Find
Valtrax Research is opening — leave your email and we'll ping you the moment the first compounds are listed.
Your cart is empty
Semax heptapeptide · ACTH(4–7) + Pro-Gly-Pro
The ACTH(4–7) fragment capped with Pro-Gly-Pro: Met-Glu-His-Phe-Pro-Gly-Pro. Supplied as a lyophilized powder for research purposes only.
Catalog opens shortly. Leave your address and we will ping you the moment this compound is orderable.
Tested lot by lot at ≥99% purity. The Janoshik certificate for your lot is emailed with the order.
Everything Valtrax Research ships is bench material for in-vitro work. None of it is a drug, a supplement, a cosmetic, or a medical device, and none of it is intended for human or animal use, ingestion, or administration. Placing an order is your confirmation that you are a qualified researcher buying for lawful research, under every Canadian law and regulation that applies to you.
Take the ACTH(4–7) fragment, which on its own has no hormonal pull on cortisol, and cap it with Pro-Gly-Pro. That is Semax: Met-Glu-His-Phe-Pro-Gly-Pro, a seven-residue peptide engineered so the active core survives enzymatic attack long enough to be studied.
The interesting move is the decoupling. By keeping a melanocortin-adjacent fragment but dropping the steroidogenic ACTH signal, the molecule was built to probe the neurotrophic and cognitive side of that peptide family in isolation — which is exactly the lane the lyophilized vial gets used in.
Semax is studied as a neurotrophic agent rather than a single-receptor drug. The consistent findings are raised BDNF and NGF expression in cortical and hippocampal tissue, alongside monoaminergic modulation; behavioral cognition tasks and ischemia/neuroprotection models supply the functional endpoints.
As a dry article, Semax lets a lab set its own solvent and route, then read the same endpoints the molecule is known for: induction of BDNF and NGF in cortical tissue, plus effects on dopaminergic and serotonergic tone. The work treats it as a neurotrophic modulator more than a classical receptor ligand.
Most of the record is Russian in origin, where Semax has been examined across cognition, attention, and ischemic-injury paradigms. The throughline is neuroprotection and neurotrophic support — what a stabilized ACTH fragment does once its hormonal signal has been engineered out.
Semax came out of the Institute of Molecular Genetics in Moscow, where researchers reworked the ACTH(4–10) region to keep a behaviorally relevant core while removing corticotropic activity. Adding the Pro-Gly-Pro tail gave the fragment the stability that earlier ACTH analogues lacked.
The lyophilized form is the original research presentation — dry peptide a lab reconstitutes to its own specification — and it remains the format behind most of the published neurotrophic and cognitive work.
Every lot is tested for identity, purity, and net content, and the certificate is emailed with the order.
Janoshik Analytical, a laboratory Valtrax does not own, runs the testing — identity by mass spectrometry, purity by RP-HPLC at ≥99%. The certificate covering the lot you receive is also emailed with your order.
Same Shelf
